Beneath is an approximation of this video’s audio content material. To see any graphs, charts, graphics, photographs, and quotes to which Dr. Greger could also be referring, watch the above video.
Parkinson’s illness is a neurodegenerative mind dysfunction that impacts hundreds of thousands of individuals. What causes it? Properly, in the event you take a look at life-style components related to Parkinson’s illness, the strongest dietary affiliation with elevated threat of Parkinson’s illness is dairy consumption. The truth is, dairy merchandise are the solely meals group that has been persistently related to a excessive threat of growing Parkinson’s. 5 giant potential research have confirmed the hyperlink…together with the 2 Harvard cohorts, the Harvard Nurse’s Well being Research and different Well being Professionals, which adopted greater than 100 thousand folks, adopted for many years, within the largest evaluation of dairy and Parkinson’s illness so far, analyzing greater than 1,000 newly identified instances––and all of the research discovered a hyperlink between dairy and Parkinson’s, most discovering a major hyperlink. About 50 % enhance in threat total in these consuming probably the most milk in comparison with these consuming the least, at a p worth of lower than 0.00001, which means lower than 1 in 100,000. You’d solely get a discovering that excessive by probability. Okay, however why is there a hyperlink in any respect?
Regardless of clear-cut associations between milk consumption and Parkinson’s illness incidence, there isn’t a rational clarification, concluded one evaluation. A yr later although, we acquired a clue. Midlife milk consumption and substantia nigra neuron density at loss of life. What does that imply? Parkinson’s is induced when a lot of the nerve cells in a important a part of the mind are killed off. And so, in the event you return and see how a lot milk folks had been consuming of their 40s, 50s, and 60s, after which take a look at their brains on post-mortem and rely what number of of these important neurons that they had left, in each single quadrant, neuron density was maximized in those that consumed no milk, and lowest in those that consumed probably the most milk. Even after eradicating the Parkinson’s instances, these consuming two cups of milk a day had as much as 40 % fewer nerve cells in that important mind area. What’s in milk that may very well be wiping out mind cells? Amongst those that drank probably the most milk, residues of the pesticide heptachlor epoxide had been present in 9 out of 10 brains. Aha, so perhaps the ﬁnding of pesticide residues extra generally within the brains of those that drank probably the most milk might clarify how milk may very well be cause-and-effect associated to Parkinson’s illness threat.
Now that’s not the one potential clarification. Bear in mind my video on how meat comprises that clumpy neurotoxic protein alpha-synuclein? Properly, dairy merchandise might include hint quantities as nicely, however we don’t have affirmation of that. Might the milk sugar galactose be the lacking hyperlink? That’s what lactose in milk breaks down into within the physique, and galactose is what’s used to induce getting older, to experimentally trigger getting older within the mind. If you drink it, the galactose is picked up by your mind inside just a few hours, and for doses above 100 mg/kg, it seems that galactose could cause pathological alterations in mind cells, just like these noticed in Parkinson’s illness. And these portions may be reached and surpassed with the straightforward each day consumption of two glasses of milk, the principle dietary supply of galactose in people. And of all of your mind cells, these dopaminergic neurons, those that you must retain to forestall Parkinson’s could also be extra susceptible to galactose-induced injury; galactose-induced oxidative stress.
Galactose may clarify the findings linking milk-drinking with larger loss of life charges. Now, chances are you’ll be pondering, nicely duh, the saturated butterfat is simply reducing folks’s life brief. However larger mortality with excessive milk consumption is noticed regardless of the milk fats content material. Skim milk is likely to be fat-free, but it surely’s not lactose-free.
Can’t you simply use lactose-free milk? What about Lactaid? That has the lactase enzyme added to make lactose-free milk. However it simply breaks down lactose into galactose within the carton reasonably than in your intestine. So, you’re nonetheless ingesting the identical quantity of galactose. No surprise then, maybe, that larger milk consumption at midlife could also be related to a larger price of cognitive decline. I imply, researchers use galactose to create mind getting older within the laboratory. Administration of D-galactose, a metabolic by-product of lactose, has been extensively used to imitate cognitive getting older by oxidative stress in animal fashions. In comparison with those that mentioned they “nearly by no means” drink milk, these consuming greater than a glass a day seem extra more likely to endure a worldwide decline of their cognitive operate.
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